June 11, 2020
OICR-funded researchers identify promising targets to shut down the spread of ovarian cancer
Despite new targeted therapies, ovarian cancers often spread to other organs in the body and become resistant to drugs, leading to nearly 2,000 deaths in Canada each year according to the Canadian Cancer Society. Dr. Trevor Shepherd is committed to finding new solutions for women with this disease.
In an initiative supported by local ovarian cancer survivors and philanthropic donors, Shepherd and collaborators have discovered a new way to shut down the spread of ovarian cancer. In their recent study published in Cancers, they found a molecular pathway that ovarian tumours require to spread to other organs. The study pinpoints two key proteins along this pathway – LKB1 and NUAK1 – as potential drug targets.Continue reading – Community-driven initiative finds new potential avenue of ovarian cancer treatment