January 12, 2018

Large-scale study provides clearer picture of recurrence risk for ER-positive breast cancer

Dr. John Bartlett

Endocrine therapy uses hormone antagonists to greatly reduce the risk of disease recurrence in women with early-stage, estrogen-receptor (ER) positive breast cancer. However, the treatment can come with severe side effects. Around 30 per cent of women stop taking the therapy after three years largely due to these negative impacts. Usually patients receive the hormone therapy for five years following initial treatment (e.g., chemotherapy, surgery), but it can also be taken longer-term. A central question facing patients and clinicians is how to balance, in their decision making, the side effects of long-term treatment with the potential reduction in recurrence risk. In short, they want to know: ‘is it worth it?’ 

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November 23, 2016

OICR and OMPRN celebrate International Pathology Day with educational events

A technician works in OICR pathology lab

On November 16 OICR and the Ontario Molecular Pathology Research Network (OMPRN) joined other organizations around the world celebrating International Pathology Day.

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August 17, 2016

Dr. John Bartlett discusses why new retrospective breast cancer study could lead to better diagnosis and treatment for patients

Fu Yan - In the lab.

OICR has announced a new retrospective study that will help to identify mutations for breast cancer, increasing understanding of the disease and potentially leading to better diagnosis in the future. The study is led by Dr. John Bartlett, Director of OICR’s Transformative Pathology Program and Dr. Harriet Feilotter, Department of Pathology and Molecular Medicine, Queen’s University. We spoke to Dr. Bartlett about why this study is important for the future of breast cancer diagnosis and treatment. 

Continue reading – Dr. John Bartlett discusses why new retrospective breast cancer study could lead to better diagnosis and treatment for patients