November 2, 2017

Novel approach yields four robust biomarkers for breast cancer drug response

Dr. Benjamin Haibe-Kains and Zhaleh Safikhani pose for a photo

Biomarkers that can help predict a patient’s response to a given drug are central to testing new therapies in clinical trials as well as selecting which drugs to use in the clinic. Some of the biomarkers in use today rely on the overall expression of a given gene to predict if a drug will be of benefit. While these types of biomarkers have aided cancer research and treatment, a group led by Dr. Benjamin Haibe-Kains recently published research that is ushering in a new class of biomarkers – those based on gene isoforms (the different expression of the same gene within an individual). This work opens the door to more precise biomarkers.

Continue reading – Novel approach yields four robust biomarkers for breast cancer drug response

August 17, 2016

Dr. John Bartlett discusses why new retrospective breast cancer study could lead to better diagnosis and treatment for patients

Fu Yan - In the lab.

OICR has announced a new retrospective study that will help to identify mutations for breast cancer, increasing understanding of the disease and potentially leading to better diagnosis in the future. The study is led by Dr. John Bartlett, Director of OICR’s Transformative Pathology Program and Dr. Harriet Feilotter, Department of Pathology and Molecular Medicine, Queen’s University. We spoke to Dr. Bartlett about why this study is important for the future of breast cancer diagnosis and treatment. 

Continue reading – Dr. John Bartlett discusses why new retrospective breast cancer study could lead to better diagnosis and treatment for patients