September 6, 2018

Q&A with Dr. Christina Yung, OICR’s new Director of Genome Informatics

OICR welcomes Dr. Christina Yung as Director of Genome Informatics. Yung is returning to OICR from the University of Chicago where she led and managed the National Cancer Institute’s Genomic Data Commons (GDC) – a unified data system that promotes the sharing of genomic and clinical data between researchers.

Continue reading – Q&A with Dr. Christina Yung, OICR’s new Director of Genome Informatics

September 4, 2018

Meet our students – 2018

Meet Dike Aduluso-Nwaobasi, Sarah Donald and Benson Wan. Find out how summer co-op positions affected their career and educational journeys.

August 22, 2018

Heliotrope: Personalizing cancer treatment decisions

Justin Cook poses for a photo in his office

OICR-developed software tool, Heliotrope, gains attention from the private sector for its potential to analyze large amounts of genomic information and inform clinical decision making

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August 22, 2018

Meet the researchers: Ratheesh Subramaniam

Ratheesh Subramaniam talks about his work in OICR’s Drug Discovery team and how it could help doctors make a difference in treating cancer patients.

August 21, 2018

Leader in data access and CEO of DNAstack, Dr. Marc Fiume, joins OICR as its newest Associate

Dr. Marc Fume poses for a photo in an atrium

Formalizing his longstanding relationship with OICR, Dr. Marc Fiume joins the Institute as an Associate to turn big data into a cure

“We know there are valuable – potentially life-saving – genomics and clinical data that are locked away in the sever rooms in hospital basements,” says Dr. Marc Fiume, CEO of DNAstack, Adjunct Professor at the University of Toronto, and OICR’s newest Associate. “We’re working to make these data more findable, accessible and useful to help researchers find cures for diseases faster than ever before.”

Continue reading – Leader in data access and CEO of DNAstack, Dr. Marc Fiume, joins OICR as its newest Associate

August 16, 2018

Researchers find common cell process key to therapy resistance

Ottawa researchers discover a new way to make cancer cells more susceptible to virus-based therapies

Over the past decade, researchers have made significant progress in designing oncolytic viruses (OVs) – viruses that destroy cancer cells while leaving healthy tissue unharmed. However, some cancer cells are resistant to this type of therapy and their resistance mechanisms remain poorly understood.

Researchers at the The Ottawa Hospital and University of Ottawa, under the leadership of Dr. Carolina Ilkow, have discovered that a common cellular mechanism, RNAi, allows cancer cells to fight back against cancer-fighting viruses. Their findings, recently published in the Journal for Immunotherapy of Cancer, show that blocking RNAi processes in tumours can make cancer cells more susceptible to OVs.

Continue reading – Researchers find common cell process key to therapy resistance

August 10, 2018

Join the OICR community in having fun and raising funds for the Terry Fox Foundation at the Great Canadian Hair “Do”

Participants of last year's event pose for a group photo.

On Friday, September 14 at noon, a team of OICR staff members and others from the community will once again take part in the one-of-a-kind Great Canadian Hair “Do” in support of The Terry Fox Foundation. The team will have their heads shaved or have their hair styled in an outrageous fashion in the atrium of the south tower of the MaRS Centre. As part of the event, the crowd will hear from a cancer survivor and a cancer researcher to learn about the importance of cancer research fundraising and funding.

Last year the team raised more than $8,500. Don’t miss out on this great opportunity to make a difference! If you are interested in participating in an unforgettable event, while helping a good cause, visit the OICR team website to register. MaRS is a community partner for the Great Canadian Hair Do.

To join the team or to donate, visit: http://www.terryfox.ca/OICRHairDo2018

 

August 7, 2018

Data integration for the future of precision oncology

CDIC Banner images

Big data are ushering in a new era of individualized cancer care and prevention, but not without conceptual and practical challenges. Canadian advances in genomics will be made by or limited by bioinformatics analytical capacity as well as the ability to store and analyze data in new and more sophisticated ways.

To help realize the potential of genomics research in cancer, the Canadian Data Integration Centre (CDIC) platform, led by OICR, offers third generation bioinformatics and genomics tools to support both functional and clinical genomics research. CDIC is the largest academic cancer informatics program in the country – offering customizable, client-oriented access services for data challenges across diverse research areas.

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August 3, 2018

Open source in open science: Accelerating cancer research (Part 2)

Part 2 of Open source software

Find part 1 here: Open source in open science: Accelerating cancer research


OICR researchers have contributed to major open source projects available to the global research community in order to accelerate cancer research. Click the link below to read about more of OICR’s open source software projects.

Continue reading – Open source in open science: Accelerating cancer research (Part 2)

August 2, 2018

Ontario centre attracts national attention for probe research, development and commercialization

Centre for Probe Development and Commercialization

The Centre for Probe Development and Commercialization (CPDC) awarded $10.5 million to expand molecular imaging probe work in Ontario

Translating new scientific discoveries into products and moving those products to the market is a challenging process. This is especially the case for highly-regulated medical products such as radiopharmaceuticals – a special class of drugs that are used to accurately diagnose and treat diseases. Over the past decade, the CPDC in Hamilton has been bridging the gap between the innovation and commercialization of radiopharmaceuticals in Ontario and, in turn, reaping benefits for patients and the province’s economy.

Continue reading – Ontario centre attracts national attention for probe research, development and commercialization

August 1, 2018

Open source in open science: Accelerating cancer research (Part 1)

Open source

In the effort to bring better disease prevention and treatment to patients faster, cancer researchers are thinking more creatively about ways to conduct high-quality scientific research. Concerns about the quality, efficiency and reproducibility of research have motivated the open science movement – the growing trend of making data, methods, software and research more accessible to the greater scientific community.

Open source software (OSS), a major component of open science, enables research groups to reduce redundant efforts in software engineering by sharing software code and methods. In addition to improving efficiency, OSS promotes high-quality research by enabling collaboration, and helps make research easier to reproduce by making it more transparent.

Continue reading – Open source in open science: Accelerating cancer research (Part 1)

July 31, 2018

Meet the researchers: Cheryl Crozier

Cheryl Crozier talks about her work in OICR’s Diagnostic Development team and how it could help doctors make a difference in treating cancer patients.

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