August 17, 2017

New genes discovered regulating brain metastases in lung cancer

Mohini SinghResearch from McMaster University has identified new regulators of brain metastases in patients with lung cancer.

These regulators are the genes called SPOCK1 and TWIST2.

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August 15, 2017

New data resource centre will help better understand links between birth defects and childhood cancer

Researchers from the Ontario Institute for Cancer Research playing major role in the design and development of the new initiative.

Toronto (August 15, 2017) – Children with structural birth defects are at a much higher risk of developing certain types of childhood cancers but scientists currently lack vital information about why this occurs.

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August 9, 2017

Mutation in prostate tumours shown to change epigenetic identity, the make-up of DNA

Prostate cancer researchers have mapped the impact of an acquired mutation that alters epigenetic identity, the make-up of DNA, in about 50 per cent of patient tumour samples. The discovery also identifies a new opportunity for targeted therapy.

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August 9, 2017

CIMTEC appoints Justin Leushner as new CEO

The Centre for Imaging Technology Commercialization (CIMTEC) has appointed Mr. Justin Leushner as Chief Executive Officer. CIMTEC was established to accelerate the development of medical imaging technology and commercialize new technologies. Leushner brings extensive experience in both the private and public sectors. Most recently he was the Vice President at the TechAlliance of Southwestern Ontario, where he and his team worked with more that 300 companies in the region.

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August 9, 2017

Importance of large database of genetic variants reinforced in a new study

A newly published paper in Genetics in Medicine has reinforced the fundamental importance of collecting information about genetic variances in a single large database.  With so much important genetic information being used globally to understand the underlying genetic influences of diseases, researchers and clinicians need an accessible repository to share this information.

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August 1, 2017

FACIT launches cross-border campaign to recruit clinical scientists and biotechnology industry executives

FACIT Logo

Initiative targets expats for growing oncology company portfolio in Ontario

TORONTO, ON (July 18, 2017) — FACIT, which commercializes innovative cancer treatments, has launched a recruitment campaign targeting individuals who possess strong clinical development, commercial and fundraising experience in the technology and life sciences sectors.  FACIT is expanding and updating its database of US-based industry advisors for roles ranging from investment diligence to full time management roles in Ontario-based biotech start-ups.  While Canadian biotechnology expatriates are the focus of this initiative, FACIT continues to attract worldwide leaders in oncology research to the province, a shared mandate well established by its strategic partner, the Ontario Institute for Cancer Research (OICR).

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August 1, 2017

FACIT announces investment in three Ontario start-ups under Prospects Fund

The logos of Radialis Medical, DNA Stack and KA Imaging

FACIT invests first round of Prospects Fund in Radialis Medical, KA Imaging, and DNAstack.

TORONTO, ON (July 10, 2017) – FACIT has announced the first three investments under its new Prospects Oncology Fund for proof-of-concept development of breakthrough cancer technologies. Ontario start-ups Radialis Medical of Thunder Bay, KA Imaging of Kitchener, and DNAstack of Toronto are the first to receive capital from this new fund, illustrating the strength and breadth of the cancer research network in the province. FACIT’s strategy is to bridge the gap in capital and expertise often experienced by early stage companies, and better position innovations to reach patients.

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July 12, 2017

Ovarian cancer research team working to exploit disease’s vulnerabilities

Drs. Amit Oza and Rob Rottapel

Given the advancements in treating many other types of cancer, it may come as a surprise that outcomes for patients with the most deadly form of ovarian cancer have not improved in 50 years. This form, known as High Grade Serous Ovarian Cancer (HGSOC), accounts for 80 per cent of ovarian cancer deaths in Canada. Surgery and chemotherapy can be effective, but ultimately three-quarters of women with HGSOC will see their disease return. To deliver better outcomes for patients, OICR has launched a new ‘all star team’ of ovarian cancer researchers.

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July 11, 2017

How OICR is helping to boost the body’s ability to fight cancer

Oncology Viruses - Image of a cell.

The body’s immune system is incredibly powerful. Its ability to detect and destroy various pathogens makes it central to maintaining good health. While we all know the role it plays in fighting the common cold or flu, many do not know that it has recently been enlisted by scientists in the fight against cancer. Researchers in a field known as immuno-oncology are working to find ways to turn on the body’s defences to locate and destroy tumour cells. OICR recently established a team of expert scientists and clinicians to develop and test new immunotherapies to help patients.

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July 11, 2017

New research group aims to exploit genomic differences within brain cancer to develop new treatments

Drs. Taylor and Dirks

This year, almost 3,000 Canadians will be diagnosed with brain cancer – one of the hardest forms of cancer to treat. In May, OICR launched its Brain Cancer Translational Research Initiative (TRI) to leverage recent insights into the genomic heterogeneity in two common types of brain cancer – Medulloblastoma (MB) and Glioblastoma Multiforme (GBM). Developing a better understanding of the genes and pathways central to MB and GBM will enable the development of new drugs and provide a much needed improvement in treatment options for patients, many of whom are children and young adults and are particularly susceptible to long-term side effects from treatment.

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July 11, 2017

New multi-disciplinary team taking a stem cell-based approach to target acute leukemia

TEchnicians work in a stem cell research lab.

The rising use of stem cell-based therapies has illustrated the power of stem cells to treat a number of diseases. Now a group of Ontario researchers are looking at the promise of stem cells from a different perspective. Amongst other efforts, they are developing and testing new therapies that target and kill leukemic stem cells to lessen the chances of acute leukemias (AL) coming back following standard treatment.

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July 11, 2017

Oncologist and OICR researcher pens step-by-step guide to getting high-quality cancer care

Dr. David Palma

As a radiation oncologist in London, Dr. David Palma spends a lot of his time speaking with patients about their treatment. But a personal experience helped him realize more needed to be done to inform patients about the importance of seeking out high-quality care, and to empower them to seek out the best care for their specific cancer. Palma, who is also an OICR clinician-scientist, just published a book called “Taking Charge of Cancer: What You Need to Know to Get the Best Treatment”, available in bookstores across North America. We spoke to Palma about the story behind the book, why such a book is needed and what he hopes to achieve with it. Palma is donating all royalties from the sales of the book to his local cancer foundation.

Continue reading – Oncologist and OICR researcher pens step-by-step guide to getting high-quality cancer care