September 25, 2017

New study uncovers the role of mitochondrial DNA in prostate cancer

An image of mitochondria

Since mitochondria are inherited maternally, it may strike some as an odd place to go looking for connections to prostate cancer. But recently an international research team explored that relationship by looking at how the small amount of DNA contained in mitochondria, a cellular structure, is involved in prostate cancer.

Continue reading – New study uncovers the role of mitochondrial DNA in prostate cancer

September 15, 2017

Some braided it, some shaved it: the 2017 Terry Fox Great Canadian Hair Do!

OICR Hair do team - After

Since 2008 OICR staff members and others from the community have come together each year for the Terry Fox Great Canadian Hair Do, to raise money for important cancer research. This year the team raised more than $8,300 in support of the Terry Fox Foundation by shaving their heads or having their hair styled and brightly coloured. With these generous contributions the event has now raised more than $120,000 since its inception, and the team is still accepting donations.

In addition to raising funds, the event also provided an opportunity to reflect on the importance of cancer research. Adam Green, who survived non-Hodgkin’s lymphoma after a diagnosis at the age of 15, shared his story with the audience noting, “I am here because of what Terry started.” Many of the participants also shared stories about how cancer has touched their lives and discussed the research they are doing to improve the diagnosis and treatment of the disease.

The photos below show how much fun this event is every year. The organizers thank everyone for their support and encourage all to get involved next year or find a Terry Fox Run near you this Sunday, September 17!

September 6, 2017

OICR launches Tissue Portal to support tissue-based research projects

Fu Yan - In the lab.

OICR’s Tissue Portal is a new central entry and exit point for human tissue derived samples handled at OICR. This will serve as a gateway for tissue-based research projects to access over 100 services and resources at OICR being made available through the OICR Collaborative Research Resources on a cost-sharing basis. The Tissue Portal will standardize and streamline the storage, processing and distribution of samples for collaborative research studies at OICR.

Continue reading – OICR launches Tissue Portal to support tissue-based research projects

September 6, 2017

Ontario Tumour Bank collaborating to improve biobanking globally

Monique Albert

Biorepositories (or biobanks) play an important role in many types of research. But biobanking is a complex process requiring careful management of a whole range of scientific, legal, technical and ethical issues. We spoke to Monique Albert, Director of the Ontario Tumour Bank, about the importance of good biobanks, how the Ontario Tumour Bank is working with international partners to improve biobanking globally and why this type of international collaboration is benefitting researchers in Ontario.

Continue reading – Ontario Tumour Bank collaborating to improve biobanking globally

September 6, 2017

Large-scale genomic study helps set new course for paediatric brain cancer research

Dr. Michael Taylor

Today’s therapies for medulloblastoma, a highly aggressive form of childhood brain cancer, bring benefits to young patients but also come with serious side effects. Dr. Michael Taylor and a team of international collaborators recently published results in Nature of an ambitious project that analyzed the genomes of around 500 cases of medulloblastoma. Their goal was to identify gene mutations that are commonly mutated in the cancer, but not in the normal cells of patients.

Continue reading – Large-scale genomic study helps set new course for paediatric brain cancer research

September 6, 2017

Innovative study brings next-generation genomic sequencing to more Ontario cancer patients

Toronto (September 6, 2017) – Understanding a cancer’s genetics is key to selecting targeted therapies that are likely to be of the most benefit to a patient. The Ontario Institute for Cancer Research (OICR) today announced a new study, called Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (OCTANE). OCTANE will use next-generation genome sequencing technology to bring a unified molecular profiling approach to five Ontario cancer centres.

Continue reading – Innovative study brings next-generation genomic sequencing to more Ontario cancer patients

August 30, 2017

Tracking glioblastoma as it develops

Dr. Peter Dirks

An international team of scientists have used an innovative barcode-like system to track the behaviour of individual glioblastoma cells, allowing them to see how the cells of this deadly form of brain cancer have successfully evaded treatment and how they spread.

Continue reading – Tracking glioblastoma as it develops

August 17, 2017

New genes discovered regulating brain metastases in lung cancer

Mohini SinghResearch from McMaster University has identified new regulators of brain metastases in patients with lung cancer.

These regulators are the genes called SPOCK1 and TWIST2.

Continue reading – New genes discovered regulating brain metastases in lung cancer

August 15, 2017

New data resource centre will help better understand links between birth defects and childhood cancer

Researchers from the Ontario Institute for Cancer Research playing major role in the design and development of the new initiative.

Toronto (August 15, 2017) – Children with structural birth defects are at a much higher risk of developing certain types of childhood cancers but scientists currently lack vital information about why this occurs.

Continue reading – New data resource centre will help better understand links between birth defects and childhood cancer

August 9, 2017

Mutation in prostate tumours shown to change epigenetic identity, the make-up of DNA

Prostate cancer researchers have mapped the impact of an acquired mutation that alters epigenetic identity, the make-up of DNA, in about 50 per cent of patient tumour samples. The discovery also identifies a new opportunity for targeted therapy.

Continue reading – Mutation in prostate tumours shown to change epigenetic identity, the make-up of DNA

August 9, 2017

CIMTEC appoints Justin Leushner as new CEO

The Centre for Imaging Technology Commercialization (CIMTEC) has appointed Mr. Justin Leushner as Chief Executive Officer. CIMTEC was established to accelerate the development of medical imaging technology and commercialize new technologies. Leushner brings extensive experience in both the private and public sectors. Most recently he was the Vice President at the TechAlliance of Southwestern Ontario, where he and his team worked with more that 300 companies in the region.

Continue reading – CIMTEC appoints Justin Leushner as new CEO

August 9, 2017

Importance of large database of genetic variants reinforced in a new study

A newly published paper in Genetics in Medicine has reinforced the fundamental importance of collecting information about genetic variances in a single large database.  With so much important genetic information being used globally to understand the underlying genetic influences of diseases, researchers and clinicians need an accessible repository to share this information.

Continue reading – Importance of large database of genetic variants reinforced in a new study